12 signs of depression in men. from Health.com

By Lisa Zamosky

More than 5 million men in the U.S. experience depression each year.

Clinical depression—in women or men—can cause sadness and a loss of interest in once pleasurable activities. But depression can sometimes manifest in different ways in different people.

"While the symptoms used to diagnose depression are the same regardless of gender, often the chief complaint can be different among men and women," says Ian A. Cook, MD, the Miller Family professor of psychiatry at the University of California–Los Angeles.